Samir Attoub Selected Research

Colonic Neoplasms (Colon Cancer)

1/2019	PTC-209 Anti-Cancer Effects Involved the Inhibition of STAT3 Phosphorylation.
5/2018	Frondoside A Enhances the Anti-Cancer Effects of Oxaliplatin and 5-Fluorouracil on Colon Cancer Cells.
1/2017	Rhus coriaria increases protein ubiquitination, proteasomal degradation and triggers non-canonical Beclin-1-independent autophagy and apoptotic cell death in colon cancer cells.
9/2008	The transforming functions of PI3-kinase-gamma are linked to disruption of intercellular adhesion and promotion of cancer cell invasion.
8/2006	Inhibition of vascular endothelial growth factor (VEGF)-165 and semaphorin 3A-mediated cellular invasion and tumor growth by the VEGF signaling inhibitor ZD4190 in human colon cancer cells and xenografts.
1/2005	Implication of STAT3 signaling in human colonic cancer cells during intestinal trefoil factor 3 (TFF3) -- and vascular endothelial growth factor-mediated cellular invasion and tumor growth.
9/2003	Synergistic cooperation between the AP-1 and LEF-1 transcription factors in activation of the matrilysin promoter by the src oncogene: implications in cellular invasion.
7/2003	Selective abrogation of the proinvasive activity of the trefoil peptides pS2 and spasmolytic polypeptide by disruption of the EGF receptor signaling pathways in kidney and colonic cancer cells.
1/2003	Trefoil peptides as proangiogenic factors in vivo and in vitro: implication of cyclooxygenase-2 and EGF receptor signaling.
9/2002	The c-kit tyrosine kinase inhibitor STI571 for colorectal cancer therapy.

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Samir Attoub Research Topics

Disease

43	Neoplasms (Cancer) 03/2024 - 07/2003
15	Breast Neoplasms (Breast Cancer) 01/2023 - 06/2006
10	Neoplasm Metastasis (Metastasis) 01/2023 - 09/2002
10	Colonic Neoplasms (Colon Cancer) 01/2019 - 09/2002
9	Lung Neoplasms (Lung Cancer) 11/2021 - 09/2008
8	Adenocarcinoma of Lung 06/2020 - 01/2013
7	Inflammation (Inflammations) 03/2023 - 07/2003
7	Adenocarcinoma 01/2022 - 11/2013
5	Colorectal Neoplasms (Colorectal Cancer) 01/2019 - 09/2002
4	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 12/2023 - 01/2013
4	Triple Negative Breast Neoplasms 05/2023 - 01/2014
3	Colitis 03/2023 - 07/2020
3	Type 2 Diabetes Mellitus (MODY) 06/2020 - 12/2015
3	Infections 11/2014 - 09/2008
2	Body Weight (Weight, Body) 07/2020 - 09/2008
1	Carcinoma (Carcinomatosis) 01/2020
1	Leukemia 01/2020
1	Pulmonary Arterial Hypertension 01/2020
1	Thrombosis (Thrombus) 01/2016
1	Necrosis 09/2013
1	Hemorrhage 09/2013

Drug/Important Bio-Agent (IBA)

11	Peptides (Polypeptides)IBA 03/2024 - 07/2003
7	Cisplatin (Platino)FDA LinkGeneric 11/2021 - 08/2006
5	frondoside AIBA 12/2021 - 10/2011
5	Proteins (Proteins, Gene)FDA Link 06/2020 - 09/2003
4	Trefoil FactorsIBA 01/2005 - 01/2003
3	PolyphenolsIBA 01/2023 - 01/2014
3	carnosolIBA 01/2023 - 01/2014
3	Transcription Factors (Transcription Factor)IBA 01/2022 - 09/2019
3	FlavonoidsIBA 12/2021 - 01/2011
3	PhytochemicalsIBA 04/2021 - 01/2011
3	VenomsIBA 06/2020 - 09/2013
3	Protein Isoforms (Isoforms)IBA 06/2020 - 01/2005
3	Antineoplastic Agents (Antineoplastics)IBA 01/2019 - 01/2011
3	Caspase 3 (Caspase-3)IBA 01/2019 - 10/2013
3	Antimicrobial Cationic PeptidesIBA 11/2014 - 01/2013
3	Trefoil Factor-3IBA 09/2008 - 01/2003
2	Volatile Oils (Essential Oils)IBA 12/2023 - 11/2022
2	Dextrans (Dextran)FDA Link 03/2023 - 07/2020
2	sodium sulfate (sodium bisulfate)FDA LinkGeneric 03/2023 - 07/2020
2	Proteasome Endopeptidase Complex (Proteasome)IBA 01/2023 - 01/2019
2	Peroxisome Proliferator-Activated Receptors (PPAR)IBA 01/2022 - 04/2021
2	thymoquinoneIBA 04/2021 - 10/2013
2	Tyrosine (L-Tyrosine)FDA Link 09/2019 - 09/2002
2	STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)IBA 09/2019 - 01/2019
2	src-Family KinasesIBA 09/2019 - 08/2006
2	Fluorouracil (Carac)FDA LinkGeneric 01/2019 - 05/2018
2	Oxaliplatin (Eloxatin)FDA LinkGeneric 01/2019 - 05/2018
2	Phosphotransferases (Kinase)IBA 05/2018 - 09/2002
2	Paclitaxel (Taxol)FDA LinkGeneric 05/2018 - 10/2011
2	Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA 05/2018 - 09/2006
2	Small Interfering RNA (siRNA)IBA 01/2018 - 01/2016
2	Estrogen ReceptorsIBA 01/2017 - 10/2011
2	Nitric Oxide (Nitrogen Monoxide)FDA Link 02/2016 - 01/2013
2	CytokinesIBA 11/2014 - 09/2008
2	SurvivinIBA 04/2013 - 01/2013
2	salinomycinIBA 04/2013 - 01/2013
2	Anti-Bacterial Agents (Antibiotics)IBA 01/2013 - 04/2012
2	Neurotensin Receptors (Neurotensin Receptor)IBA 09/2006 - 06/2006
2	Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA 08/2006 - 01/2005
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 08/2006 - 01/2005
2	spasmolytic polypeptideIBA 07/2003 - 01/2003
1	Monoterpenes (Monoterpenoids)IBA 12/2023
1	taxaneIBA 05/2023
1	BenzopyransIBA 05/2023
1	LigandsIBA 03/2023
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 03/2023
1	EucalyptolIBA 03/2023
1	Monocyclic SesquiterpenesIBA 01/2022
1	bisabolol (levomenol)IBA 01/2022
1	buteinIBA 12/2021
1	Dichloroacetic AcidIBA 11/2021
1	Pyruvate Dehydrogenase Acetyl-Transferring KinaseIBA 11/2021
1	nerolidolIBA 07/2020
1	Sulfasalazine (Azulfidine)FDA LinkGeneric 07/2020
1	Drinking WaterIBA 07/2020
1	AntioxidantsIBA 07/2020
1	Phospholipases A2 (Phospholipase A2)IBA 06/2020
1	Glucose (Dextrose)FDA LinkGeneric 06/2020
1	Insulin (Novolin)FDA Link 06/2020
1	Endothelin Receptors (Endothelin Receptor)IBA 01/2020
1	ambrisentan FDA Link 01/2020
1	Endothelins (Endothelin)IBA 01/2020
1	Growth Factor ReceptorsIBA 09/2019
1	Interleukin-6 Receptors (Interleukin 6 Receptor)IBA 09/2019
1	plasticinIBA 04/2019
1	CamptothecinIBA 01/2019
1	PTC-209IBA 01/2019
1	DiterpenesIBA 01/2019
1	TriterpenesIBA 05/2018
1	GlycosidesIBA 05/2018
1	Gemcitabine FDA Link 05/2018
1	Cytotoxins (Cytolysins)IBA 05/2018
1	ferumoxtran-10 (ultrasmall superparamagnetic iron oxide)IBA 01/2016
1	Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA 08/2015
1	snake venom neurotoxin FIBA 01/2014
1	Silicon Dioxide (Silica)FDA LinkGeneric 01/2014
1	Hymenochirus boettgeri hymenochirin-1BIBA 11/2013

Therapy/Procedure

15	Therapeutics 11/2022 - 09/2002
2	Immunotherapy 01/2019 - 09/2008